Avalide (irbesartan, hydrochlorothiazide) is used to treat hypertension in patients who are not responding well to a single treatment. This product contains two anti-hypertension ingredients, each of which are good high blood pressure treatments in their own right.

Depending on location patients may buy Avalide under the name Co-Aprovel.

This product is generally suitable for patients age 18 and up. It can be used in children, but doctor involvement is needed to determine dosage and to monitor for developing side effects.

Avalide Basics

While some individuals may buy Avalide for other purposes, the overwhelming majority use it to treat hypertension (high blood pressure). Untreated hypertension can have a devastating effect on the cardiovascular system, leading to a lower quality of life and possibly the end of life. Hypertension is notorious for being symptom-free until a catastrophic medical event occurs---be sure to take anti-hypertension medications as directed even if otherwise feeling fine.

Avalide lowers blood pressure significantly. It has two ingredients, each an effective anti-hypertension agent in its own right:

• Irbesartan is an angiotensin II receptor antagonist which, among other things, widens blood vessels. This allows for increased blood flow and reduces the heart's workload.
• Hydrochlorothiazide (HCTZ) is a thiazide diuretic, which eliminates salt and water from the body through urine. This reduces overall blood volume and lowers blood pressure.

Combined, the medication relaxes blood vessels, reduces overall blood volume, increases oxygen delivery to the heart, and reduces the heart's workload. These are all very beneficial in patients who have high blood pressure.

Managing High Blood Pressure

Avalide comes in tablets, taken once per day with or without food as desired. Tablets should be swallowed whole and not be crushed, split, or chewed.

There are three scenarios in which a patient may start to buy Avalide:

• The patient is already taking irbesartan and HCTZ separately and wishes to combine them in a single tablet.
• The patient is already taking either irbesartan or HCTZ but needs another medication to fully control blood pressure.
• The patient isn't taking anything for blood pressure but will likely need two medications to control it.

Patients can buy Avalide in three strengths; 150/12.5 mg, 300/12.5 mg, and 300/25 mg irbesartan/hydrochlorothiazide. Which tablet is taken depends on why a patient is taking Avalide.

If individual components were both taken separately:

• Take the same amounts in Avalide, or as close as possible.
• Dosage adjustments are unlikely to be needed.

If taking one component and adding another:

• Take Avalide in the same strength as the ingredient already being taken and the lowest dose of the new ingredient.
• Dosage adjustments may be required after two to four weeks.

If starting hypertension therapy for the first time:

• Start with 150/12.5 mg irbesartan/hydrochlorothiazide.
• After two to four weeks, dosage may be increased to 300/12.5 mg or 300/25 mg, if needed according to patient response.

It takes two to four weeks of regular treatment for full benefit to be seen, hence the wait time before adjusting dosage. Patients should wait at least a couple of weeks before evaluating Avalide.

Patients with hypertension are usually encouraged to also make lifestyle changes; quitting smoking, losing weight, avoiding undue stress, and so forth. Sometimes lifestyle changes are sufficient to reduce or eliminate dependency on medications to control blood pressure. If they're not, patients will likely need to buy Avalide or similar anti-hypertension medications for the remainder of life.

Experience the Kiwi Drug Difference

Kiwi Drug is New Zealand's oldest and most-trusted online pharmacy. Our world-class customer care and expedited ordering system ensures the purchasing process is discreet, fast, and hassle-free from any location. We utilize state-of-the-art security software to ensure your data is kept safe, and we will never share your information with any third parties.

A prescription is needed to buy Avalide from Kiwi Drug. If you don't have one, our online doctor may be able to issue one to qualifying clients; simply add the desired product to your cart, begin checkout, and answer the questions on the following page. There is no charge for our online doctor services.

Patients who already have a prescription to buy Avalide will be provided with options to transfer it to us after completing checkout.

If you have any questions or need help with your order, please don't hesitate to let us know.